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Da-Gan Mao

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Open access Oct 2026

FGF7 Polymorphisms, Especially Chr7:57803771:C>T, Are Associated with Lambskin Traits in Hu Sheep

Lambskin quality is an economically important trait in Hu sheep (Ovis aries), with wool-pattern characteristics contributing substantially to commercial value. However, the genetic basis of lambskin variation remains incompletely understood. This study evaluated single nucleotide polymorphisms (SNPs) in four candidate...

K. Beshah, Jing Xie, Da-Xiang Wang et al. · 0 citations
Sep 2026

MiR-130b-3p regulates steroidogenesis-related markers, cell viability, inflammation, oxidative stress, and pyroptosis-associated responses by targeting PPARG in LPS-exposed goat granulosa cells.

LPS, an endotoxin derived from Gram-negative bacteria, disrupts granulosa cell (GCs) function, and impairs ovarian activity. This study aimed to investigate the role of miR-130b-3p targeting PPARG expression in LPS-exposed goat GCs. Results indicated that LPS decreased PPARG expression, while increased the level of miR...

Jie Zhao, Jing Xie, Xi Wang et al. · 0 citations
Open access Aug 2026

Whole-Genome Resequencing Reveals Selection Signatures Associated With Lambskin Patterns in Hu Sheep.

In China, Hu sheep lambskin quality is largely determined by wool curvature, with wavy-wool lambs producing higher-quality pelts than straight-wool lambs. However, the genetic mechanisms underlying wool curvature formation remain poorly understood. To address this knowledge gap, we conducted whole-genome resequencing a...

K. Beshah, Jing Xie, Muhammad Tariq et al. · 0 citations

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