Open access
Oct 2026
Region-specific cellular ecosystems govern divergent remodelling trajectories in hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) exhibits marked regional heterogeneity despite shared sarcomere gene mutations. The molecular basis underlying preferential septal hypertrophy and relative apical preservation remains poorly understood. To define region-specific cellular programs and intercellular signalli...
Y. Tan, Z. Wang, Y. Song et al.
· European Heart Journal · 0 citations