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Open access Jul 2026

Efficacy and safety of early combined therapy with PCSK9 inhibitor and statin in acute ischemic stroke (CAPTAIN): protocol of a multicenter, prospective, open-label, randomized trial

This study is expected to provide evidence on the efficacy and safety of the early addition of a PCSK9 inhibitor to statin therapy in patients with AIS attributable to sICAD.

H. Qiu, Y. Xie, S. Xiong et al. · 0 citations
Open access Sep 2026

Impact of stepwise dual antiplatelet therapy de-escalation in patients with multivessel disease undergoing drug-coated balloon angioplasty: insights from the REC-CAGEFREE II trial

Among patients with ACS undergoing DCB-only angioplasty, those with multivessel disease were associated with a higher risk of NACE than those with single-vessel disease and stepwise DAPT de-escalation and standard DAPT exhibited similar risk-benefit profiles in both subgroups.

C. Gao, Y. Zhang, X. He et al. · 0 citations

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