Plastic pollution is an emerging yet understudied environmental risk to the immune system. Once ingested, microplastic and nanoplastic particles (MNPs) can translocate from the gut to internal organs1-3, with macrophages serving as primary targets4. Kupffer cells (KCs), the liver-resident macrophages, have a central ro...
Nikola Makdissi, Maria Francesca Viola, L. Steinheuer et al.· Nature Metabolism· 0 citations
Manual expert gating remains common practice for defining specific cell populations in flow cytometry data, but increasing numbers of measured parameters and high inter-rater variability limit consistency across studies. Cluster-based approaches use the full marker space to define cell populations more consistently, bu...
V. Friedrich, Karola Mai, T. Hofer et al.· Nature Communications· 0 citations
Emerging evidence indicates that cell-type-specific and temporally dynamic ciliary signatures determine signalling competence and disease susceptibility, and defining these signatures and the mechanisms that regulate their plasticity could lead to new therapeutic opportunities for ciliopathies and other cilia-associate...
O. K. Thomsen, Gaia Pigino, L. B. Pedersen et al.· Nature Reviews Nephrology· 0 citations
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