Kidney transplant recipients develop disorders of mineral and bone metabolism that further impair bone strength, leading to osteoporosis and a high fracture risk. However, evidence in this setting is limited. Romosozumab, a sclerostin inhibitor with both anabolic and antiresorptive effects, is an attractive option, but...
Simona Barbuto, Paolo Mastromauro, G. Zavatta et al.· Frontiers in Endocrinology· 0 citations
Background. Older adults represent a growing proportion of kidney transplant (KT) recipients, but early posttransplant morbidity remains substantial. We aimed to identify pretransplant factors associated with a complicated early posttransplant course in recipients aged ≥65 y and to assess its impact on subsequent outco...
D. Vetrano, E. Gessaroli, V. Corradetti et al.· Transplantation Direct· 0 citations
BACKGROUND
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have become the standard of care in managing chronic kidney disease (CKD) and heart failure (HF), both in patients with and without type 2 diabetes mellitus (T2DM). Nonetheless, identifying those at persistent high cardiovascular (CV) and renal risk remains...
I. Capelli, D. Vetrano, D. Ribichini et al.· JN. Journal of Nephrology (M...· 0 citations
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