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Author

D. Tychinin

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Open access Sep 2026

Comparative Single-Nucleus Transcriptomic Analysis of the Intact Left Ventricle in Acomys cahirinus and Mus musculus

Background/Objectives: Acomys cahirinus exhibits more favorable cardiac remodeling after ischemic injury than Mus musculus, yet the molecular organization of the intact myocardium remains poorly characterized. This study aimed to identify baseline interspecies differences in the adult left ventricle, with particular em...

Nikita Filatov, Kirill Kokorichev, D. Tychinin et al. · 0 citations
Open access Jul 2026

Congenital heart defects genetic architecture in a small cohort: an integrated approach to prioritizing variants

This study expands the understanding of the genetic landscape underlying congenital heart anomalies and emphasises the need for larger, deeply phenotyped cohorts to translate preliminary insights into clinically applicable predictors.

A. Korobeinikova, E. Petriaikina, D. Tychinin et al. · 0 citations
Review Open access Jul 2026

Biomarkers of treatment response in rheumatoid arthritis: from conventional markers to tissue immunophenotype

It is concluded that precision medicine in RA will require integrated biomarker panels combining clinical, pharmacological, molecular, and synovial tissue data, and the development of scalable, externally validated, and clinically interpretable models capable of assigning synovial endotypes and supporting mechanism-bas...

N. A. Batashkov, E. Gerasimova, D. Gerasimova et al. · 0 citations

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