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Open access Aug 2026

Development of Rest-Activity Rhythms in Infancy and Their Disruption in Infantile Epileptic Spasms Syndrome

Background and Objectives: In persons with epilepsy, seizure risk is tightly linked to the health of sleep and circadian rhythms. Rest-activity rhythms (RARs), derived from continuously worn activity monitors, can provide objective assessments of diurnal patterns of activity. Compared with healthy controls, adults with...

R. El Atrache, S. Karedia, N. Adhyapak et al. · 0 citations
Review Open access Aug 2026

Management of Infantile Epileptic Spasms Syndrome: A survey of US pediatric hospitals

Evaluating the management practices of Infantile Epileptic Spasms Syndrome across tertiary pediatric hospitals in the United States found areas of consensus (use of overnight video EEG at initial diagnosis, use of high‐dose prednisolone as initial treatment, preference for sequential as opposed to combination therapy,...

Akshat Katyayan, Christina Briscoe, Sonam Bhalla et al. · 0 citations

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