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D. Stoyanov

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Review Open access Jul 2026

Unifying the hallmarks of major depression through neuroimmune–metabolic–oxidative (NIMETOX) dysregulation: a mechanistic systems framework

Evidence is presented that peripheral NIMETOX pathways may lead to neuroinflammation, microglial activation, and neuronal damage and that increased lipid load impairs these central pathways, as well as evidence that peripheral NIMETOX pathways may lead to neuroinflammation, microglial activation, and neuronal damage.

Michael Maes, A. Almulla, Drozdstoj Stoyanov et al. · 0 citations

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