Author

D. Shi

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Open access Sep 2026

Compound Ciwujia Granules Attenuate Stress‐Induced Anxiety‐ and Depression‐Like Behaviors via Inhibition of TNF‐α‐Associated Neuroinflammation in the dmPFC

ABSTRACT Aims Compound Ciwujia Granules (CWJ) have shown antidepressant‐like effects, but the neural and molecular mechanisms underlying these effects remain unclear. This study aimed to investigate the mechanisms by which CWJ ameliorates anxiety‐ and depression‐like behaviors. Methods A 6‐week chronic unpredictable mi...

Fei Tian, Yi Li, Meng-Yu Dai et al. · CNS Neuroscience & Therapeut... · 0 citations

Open access Sep 2026

137. Succinate induces compulsive-like behavior via medial prefrontal cortex glutamatergic neuron excitation-inhibition imbalance in male mice

Abstract Background Obsessive-compulsive disorder (OCD), a disabling psychiatric disorder characterized by obsessions (commonly anxiety-associated) or compulsions, remains mechanistically elusive, which hinders therapeutic development. Our previous study revealed elevated succinic acid levels in both the serum of OCD p...

Y. Li, Y.-D. Zhang, X.-Y. Wu et al. · International Journal of Neu... · 0 citations

Open access Sep 2026

512. Oxytocin-receptor neurons in mPFC in stress-induced anxiety behaviors

Abstract Background The hypothalamic neuropeptide oxytocin (Oxt) modulates diverse social and anxiety-related behaviors. These biological actions are mediated by specific Oxt receptors (Oxtr), members of the G protein-coupled receptor (GPCR) family. While the medial prefrontal cortex (mPFC) is fundamental in regulating...

D. Shi, Z. Wang · International Journal of Neu... · 0 citations