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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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D. Schepmann

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Open access Aug 2026

Negative allosteric modulation of NMDA receptors with GluN2B subunit: synthesis of γ-amino alcohols embedded in a 1-benzoxepine scaffold

Novel ligands for the ifenprodil binding site of NMDA receptors with GluN2B subunit were designed, synthesized and pharmacologically evaluated. Derived from potent negative allosteric modulators, the γ-amino alcohol pharmacophore was conformationally restricted by embedding it into a 1-benzoxepine ring. Furthermore, th...

Felicitas Wendling, Yuan Chang-Halabi, Judith Schmidt et al. · 0 citations

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