CAR-T Cell Therapy in Nephrology: Evidence Across Immune-Mediated Kidney Diseases and Plasma Cell Dyscrasias, Renal Toxicity, and Patient Monitoring
In many immune-mediated kidney diseases, tissue injury is driven by dysregulated B-cell immunity, with autoantibodies and complement acting as key effectors at the glomerulus. Corticosteroids and conventional immunosuppressants control these diseases only in part, and they do so at the price of cumulative toxicity and...