INTRODUCTION
Sirtuins (SIRT1-7) are NAD+-dependent lysine deacylase and mono-ADP ribosyl transferase enzymes that integrate metabolic status with epigenetic regulation, genome maintenance, mitochondrial homeostasis, and adaptive stress responses. Their dysregulation is implicated in cancer, neurodegeneration, cardiomet...
Emanuele Fabbrizi, G. Hailu, Andrea Mancini et al.· Expert opinion on therapeuti...· 0 citations
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