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BMI SDS significantly blunts peak GH response and increases the likelihood of a GHD diagnosis, suggesting that adiposity predominantly impairs an already compromised somatotropic axis.
Growth hormone deficiency (GHD) is a frequent cause of impaired linear growth and may also affect skeletal development and bone mass acquisition. This narrative review summarizes the current evidence on bone health in pediatric GHD, with a focus on clinical findings, response to recombinant human growth hormone (rhGH)...
Background/Objectives: Autoinflammatory syndromes are defined by episodes of recurrent fever driven by innate immune dysregulation, yet their long-term organ consequences remain largely underestimated, mostly in children. Renal AA amyloidosis represents the most perilous complication of sustained, even subclinical, inf...
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