Open access
Aug 2026
CD24 Acts as an Evolutionarily Conserved Innate Immune Checkpoint in Colorectal Cancer
CD24 is identified as an innate immune checkpoint that protects colorectal tumors from macrophage-mediated clearance through an evolutionarily conserved recognition mechanism, and its loss enables them to adopt a highly motile, tumor-directed, and functionally engaged state, characterized by increased fusion activity a...
A. Machado, Cátia Rebelo de Almeida, Catarina M. Azevedo et al.
· bioRxiv · 0 citations