Bivalirudin Versus Heparin and Protamine in Adult Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-Analysis.
OBJECTIVES To summarize the evidence on the morbidity, mortality, and transfusion requirements of adult patients undergoing cardiac surgery using bivalirudin for anticoagulation compared to unfractionated heparin (UFH). MEASUREMENTS AND MAIN RESULTS A total of 407 patients in three randomized controlled trial (RCTs)...