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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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D. Pöhlmann

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2 papers indexed here

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Open access Sep 2026

T-Cell Specific Deletion of PTPN23 Alters T-Cell Development and TCRαβ/γδ Composition

Highlights What are the main findings? T-cell–specific deletion of PTPN23 causes a marked reduction in T-cells, accompanied by preferential accumulation of TCRγδ T-cells and enrichment of differentiated effector/memory T-cell subsets. Multi-omics and single-cell RNA sequencing reveal alterations in T-cell developmental...

Rocio Sanchez Alvarez, M. Determann, L. Linzmeier et al. · 0 citations
Open access Sep 2026

PTPN23 Overexpression Is Associated with Reduced Proliferation and Tumor Growth in Murine Models of Colorectal Cancer

Protein tyrosine phosphatases (PTPs) are key regulators of intracellular signaling cascades involved in cell growth, proliferation, differentiation, inflammation, and cancer. PTPN23, a non-receptor PTP, is involved in endosomal sorting and thereby regulates the internalization of growth factor receptors, such as the ep...

Rocio Sanchez Alvarez, C. Gottier, A. Montalban-Arques et al. · 0 citations

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