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D. Park

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Review Open access Aug 2026

Advances in antisense technology for cardiovascular drug discovery: from gene silencing to therapeutics

The principles that shape cardiovascular ASO candidate development are discussed, with emphasis on mechanism selection, chemical design, and exposure feasibility, and sequence optimization with exposure-informed target qualification and therapeutic-index engineering throughout ASO candidate selection.

D. Park, Anja Bühler, Christian Schöllhorn et al. · 0 citations

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