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Open access Oct 2026

Sputum and oral microbiota profiles are associated with long COVID severity and phenotype post-hospitalisation: a UK multicentre, prospective cohort study.

BACKGROUND Acute COVID-19 alters the airway microbiota. Whether these changes persist post-COVID-19 and contribute to long COVID is unknown. We aimed to describe the microbiota by long COVID severity and subtype, and identify links with inflammation. METHODS Adults were prospectively recruited to the longitudinal UK...

Daniela Alferes de Lima Headley, H. Richardson, C. Hennayake et al. · 0 citations
Review Open access Aug 2026

Evaluating non-invasive respiratory samples for bacterial and viral pathogen detection by Nanopore metagenomics in community-acquired pneumonia

Objectives: Metagenomic sequencing offers an unbiased alternative to classical microbiological diagnostic techniques, and recent advances in Nanopore sequencing technology have made real-time pathogen detection feasible. We evaluated Nanopore metagenomic sequencing in community-acquired pneumonia (CAP) patients for the...

M. Behruznia, N. Cumley, S. Quarton et al. · 0 citations
Review Open access Sep 2026

The utility of focused transthoracic echocardiography in preoperative assessment: a systematic review and narrative synthesis of current evidence.

We aimed to evaluate the feasibility, diagnostic yield, accuracy, impact on management and clinical outcomes of focused transthoracic echocardiography (fTTE) in preoperative assessment. Medline, Embase and Cochrane Trials were searched to 19 January 2026. Studies evaluating preoperative fTTE were included. Cardiac surg...

W. McIver, Sadie Dillon, Keelie Schofield et al. · 0 citations

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