Suicidal ideation and attempts are common in first-episode psychosis (FEP), but less is known about how these outcomes change in large, community-based, coordinated specialty care (CSC) settings. This longitudinal cohort study examined 2951 individuals with FEP enrolled in 87 CSC clinics across 15 states in the Early P...
S. N. Tayfur, Zhi-Qian Song, Fang-Yong Li et al.· BJPsych Open· 0 citations
Background and Hypothesis: First-line antipsychotics are ineffective in ~40% of people with first episode psychosis (FEP). Electroencephalogram (EEG)-based predictive biomarkers could be a scalable solution to reduce trial-and-error. Study Design: We acquired EEG in 56 minimally treated FEP individuals before treatment...
J. M. Rubio, M. Murphy, W. Vodovozov et al.· medRxiv· 0 citations
Impairments in processing speed and verbal learning are well documented in chronic schizophrenia and first episode psychosis (FEP), but the extent to which these patterns generalize to the clinical high-risk (CHR) stage remains less clear. A central interpretive challenge in CHR samples is the prominence of nonpsychoti...
Jonah Loshin, A. Culbreth, Abigail Stein et al.· Schizophrenia Research· 0 citations
Dopaminergic hyperactivity may be a key mechanism for core psychotic symptoms in many patients, but it is unlikely that dopamine dysregulation is a universal final common pathway across symptom domains.
M. Keshavan, Henry A. Nasrallah, A. Abi-Dargham et al.· JAMA psychiatry· 0 citations
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