Receipt of Extended-Release Opioids After Total Hip or Knee Arthroplasty and Subsequent Persistent Postoperative Opioid Use and Health System Utilization: A Population-Based Comparative Effectiveness Analysis.
BACKGROUND Extended-release opioids (EROs), continue to be used for acute pain following surgery despite guideline recommendations discouraging their use. We examined the association of filling a new postoperative ERO prescription with persistent postoperative opioid use (PPOU), clinical events, and health system outco...