Author

D. Luppov

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Open access Sep 2026

Integrated Cell-Based Transcriptomic and Pathway Profiling Enables Scalable Functional Screening of Bioactive Microalgal Extracts

Background: Microalgae and cyanobacteria represent a largely unexplored source of bioactive compounds, but systematic screening of extensive strain collections is limited by the cost and complexity of conventional chemical and pharmacological characterization. Here, we evaluated a scalable functional screening strategy...

Boris Sorokin, Anton A. Buzdin, D. Luppov et al. · Pharmaceuticals · 0 citations

Open access Sep 2026

VDJdb in 2026: boosting T-cell receptor recognition evidence using paratope embeddings and AI-based structure prediction.

We present a significant update to VDJdb, introducing substantial enhancements to both the data content and the technical infrastructure. The integration of steadily accumulating T-cell receptor (TCR):epitope recognition data, together with advances in high-throughput experimental techniques, has expanded the landscape...

D. Luppov, Anna E. Koneva, Dmitry V. Bagaev et al. · Nucleic Acids Research · 1 citation