D. Lubelski

Characterizing intradural spinal metastasis in the metastatic cascade: clinical course, dissemination timing, and molecular features in 69 patients

Frailty versus neurologic severity as predictors of perioperative outcomes among patients undergoing surgery for degenerative cervical myelopathy.

Among surgically treated patients with DCM, after accounting for DCM disease severity, frailty does not independently predict postoperative discharge disposition, suggesting that mJOA-based impairment may be a more relevant determinant of perioperative outcomes than frailty and should be prioritized in risk stratificat...

The effects of postoperative neurological deficits on overall survival in patients with malignant peripheral nerve sheath tumors.

OBJECTIVE Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas with peripheral nerve differentiation. Surgical management of MPNSTs entails wide resection with negative margins, although the extent of resection required to achieve oncological control may result in postoperative neurological morbidi...

Impact of oncological biomarkers and clinical factors on survival outcomes in renal cell carcinoma with spinal metastasis: a retrospective analysis.

Immunohistochemical biomarkers, particularly CK7, AE1/AE3, CAM5.2, and EGFR, hold significant prognostic value in RCC spinal metastasis and can help stratify patients into high- and low-risk groups, and integrate into tree-based machine learning models provides interpretable data-driven decision tools to support person...

A predictive tool incorporating frailty scores for perioperative risk assessment in patients with spinal metastasis: a national retrospective cohort study.

Integrating serum albumin, hematocrit, BMI, spinal region, and procedure type with frailty indices enhances risk stratification and informs surgical planning, preoperative optimization, and patient counseling in this vulnerable population of patients.