Author

D. Liu

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Open access Sep 2026

Lifelong Invertebrate Chordate Central Nervous System Regeneration is Driven by a Migrating Pool of Conserved Neural Stem Cells program

Adult central nervous systems (CNS) are generally constrained by limited cellular replacement. How regenerating organisms integrate structural maintenance with continuous, cyclic renewal remains unresolved. Here, we leverage the colonial chordate Botryllus schlosseri which completely resorbs and regenerates its entire...

Chiara Anselmi, Tom Levy, Jiamu Chester Yu et al. · bioRxiv · 0 citations

Jul 2026

Somatic mutations reveal the ontogeny of microglia in human ageing.

An approach that uses the collection of accumulated somatic mutations that uniquely labels each clone of cells to track the infiltration of bone-marrow-derived cells into the human brain finds evidence of an influx of bone-marrow-derived cells into the brain in all examined individuals.

Julia A. Belk, Yao-Wen Zhang, Emily E. Reilly et al. · Nature · 2 citations