Sep 2026
Beyond NAMs versus animal models: Context of use as the governing framework for integrated nonclinical strategies in drug development.
New approach methodologies (NAMs) originated in chemical hazard assessment, where two forces operate together: the scale of characterizing many substances, and a long-standing ethical and legal commitment to replacing animal testing. Drug development is weighted differently. It is a translational and decision problem a...
Stefano Gaburro, B. Berridge, Nicholas W. Kelley et al.
· Regulatory toxicology and ph... · 0 citations