Author

D. Leffa

h-index 27 View on Semantic Scholar

We have 3 of 171 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Sep 2026

Age at Diagnosis and Clinical and Genetic Profiles Among Adults With Attention-Deficit/Hyperactivity Disorder

Key Points Question Do demographic, clinical, and genetic profiles of adults diagnosed with attention-deficit/hyperactivity disorder (ADHD) in adulthood differ from adults diagnosed with ADHD in childhood or adolescence, and how do profiles of both groups compare with matched controls without ADHD? Findings In this cro...

D. Leffa, Guilherme Bauer-Negrini, B. Bellaver et al. · JAMA Network Open · 0 citations

Open access Sep 2026

Astrocyte reactivity identifies p-tau217-positive individuals at elevated risk of cognitive decline across the Alzheimer’s disease continuum

It is shown that elevated plasma GFAP significantly modulates the association between p-tau217 and both cross-sectional cognitive severity and longitudinal clinical decline, and support that astrocyte reactivity is associated with greater cognitive impairment and faster clinical decline among individuals with elevated...

B. Bellaver, G. Povala, P. C. L. Ferreira et al. · Molecular Neurodegeneration · 0 citations

Open access Jul 2026

Altered T1w/T2w-FLAIR Ratio in White Matter Hyperintensities as an Indicator of Structural Integrity Loss: Association with Alzheimer’s Disease and Vascular Dementia

Residualized WMH T1w/T2w-FLAIR ratio captures lesion-specific microstructural variation missed by volumetric measures, consistent with vascular-gliotic injury in VD and coexisting amyloid-linked demyelination in AD.

Rushil Srirambhatla, J. Campion, T. Desmidt et al. · medRxiv · 0 citations