Author

D. Lauffenburger

2 papers indexed here

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Open access Aug 2026

Maternal and fetal cellular programs orchestrate pregnancy complications and placental tolerance

The placenta is a transient organ that orchestrates maternal-fetal interactions essential for healthy pregnancy, yet the multicellular principles governing placental dysfunction remain poorly understood. Here, we present a multimodal single-cell atlas of the human placenta, profiling over 1.2 million cells from 68 dono...

R. Normand, P. L. Lopez Zapana, L. Shook et al. · medRxiv · 0 citations

Open access Jul 2026

T Cells at the Maternal—Fetal Interface: Placental Dynamics in Healthy and Complicated Pregnancy 2260996

It is found that the majority of the placental T cells are maternal and that the fetal T cells are only naïve or unconventional T cells (γδT cell subsets and MAIT cells).

R. Normand, P. L. Lopez Zapana, Daehee Han et al. · Journal of Immunology · 0 citations