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D. Korneev

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Open access Aug 2026

Genetic screening algorithm for children with medulloblastoma: a scoring system for stratifying the risk of hereditary variants

Introduction . Medulloblastoma is the most common malignant central nervous system tumor in children, representing a molecularly heterogeneous group of neoplasms (SHH, WNT, Group 3, Group 4 subtypes). Germline mutations in predisposition genes (PTCH1, SUFU, TP53, APC, BRCA2, PALB2, ELP1, GPR161) are identified in 5–...

T. I. Meshcheryakova, O. Zheludkova, T. V. Kozhanova et al. · 1 citation

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