Open access
Sep 2026
Astrocytic synapse engulfment is differentially controlled by APOE genotype.
APOE gene variants encoding the apolipoprotein E (ApoE) protein are strong genetic modifiers of risk of Alzheimer's disease (AD) with the APOE ε4 allele (APOE4) associated with substantially increased disease risk, APOE ε2 allele (APOE2) associated with decreased risk and APOE ε3 allele (APOE3) considered neutral. Rece...
Sowmya Sekizar, K. Holt, Sharon Meyers et al.
· Neuroscience · 0 citations