Open access
Oct 2026
Semaglutide reduces volume overload and atrial remodelling in a novel experimental model of cardiometabolic HFpEF
Heart failure with preserved ejection fraction (HFpEF) is an increasingly prevalent cardiometabolic syndrome linked to obesity, type 2 diabetes, and hypertension. Recent trials, including STEP-HFpEF1 and SUMMIT2, demonstrate that glucagon-like peptide-1 receptor agonists (GLP-1RAs) improve outcomes in obese HFpEF...
J. Thomas, S. Bailey, R. Nuon et al.
· European Heart Journal · 0 citations