Open access
Sep 2026
Heterogeneity in the response to the metabolic environment drives fosfomycin heteroresistance
Heteroresistance is a form of antibiotic resistance in which a phenotypically unstable subpopulation of resistant cells coexists with a majority susceptible population. Many mechanisms of heteroresistance are unclear and the impact of the extracellular environment on this phenomenon is unknown. Studying fosfomycin hete...
Jacob E. Choby, D. Hufnagel, Mu-Qing Ma et al.
· Nature Communications · 0 citations