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Open access Oct 2026

Diastolic dysfunction and structural response to SGLT2 inhibition in chronic kidney disease: the DECODE-CKD trial

Chronic kidney disease (CKD) is associated with abnormalities in diastolic function, predisposing to heart failure with preserved ejection fraction (HFpEF). In DECODE-CKD, dapagliflozin induced significant left ventricular mass index (LVMI) regression in patients with CKD, representing a novel structural cardiac...

K. Bartholdy, N. Johansen, D. Modin et al. · 0 citations
Open access Oct 2026

Dyskalemia, cardiac structure and function, and risk of adverse cardiovascular events in patients with chronic kidney disease

Dyskalemia is common in patients with chronic kidney disease (CKD) and has been associated with adverse outcomes in cardiovascular patient populations. However, the connection between plasma potassium levels, cardiac structure and function, and risk of cardiovascular events in patients with CKD remains incomplete...

I. Lenz, J. Christensen, L. Duus et al. · 0 citations

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