Autoimmune diseases represent a major and growing health burden, particularly among young adults. Emerging evidence suggests that changes in the environment and diet may contribute to disease. Experimental studies have demonstrated that excessive salt intake can modulate immune function by inducing pathogenic pro-infla...
V. Driessen, Margarita Dominguez-Villar, D. Hafler et al.· European Journal of Immunolo...· 0 citations
A single cell atlas of middle temporal gyrus revealed a unique cellular-level view of sex-specific transcriptional changes in AD, illuminating GWAS identification of sex-specific AD genes.
Le Zhang, Tian-Yu Liu, Chuan He et al.· Journal of Alzheimer's Disea...· 1 citation
It is found that anti-CD20 B cell depletion was associated with increased frequencies of regulatory mucosal-derived IgA-producing B cells in the periphery and CSF, together with increased B cell receptor clonal overlap between mucosal and systemic compartments, indicating enhanced trafficking of IgA B cells from gut mu...
T. Neziraj, Elisabeth Pössnecker, Angela A. Wang et al.· Science Translational Medici...· 0 citations
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