Author

D. Grün

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Open access Aug 2026

BARe-seq enables high-throughput dissection of cis-regulatory control of transcriptional bursting

Transcriptional bursts determine RNA output through two kinetic parameters: burst size and burst frequency. How cis-regulatory DNA encodes these kinetic parameters remains unclear, in part because existing approaches do not combine scalable sequence perturbation with allele-resolved burst inference. Here, we developed...

Franziska K. Lorbeer, Reyna Edith Rosales Alvarez, Katharina Bergauer et al. · bioRxiv · 0 citations

Preprint Jul 2026

Single-Snapshot Inference of Network Couplings from Universal Dynamics at Relative Equilibrium

Many real-world systems can be modelled as complex networks whose collective behaviour is governed by hidden interactions between nodes. Existing methods for inferring these interactions typically require controlled perturbations, time-resolved observations or multiple independent snapshots, all of which are often unav...

Moritz Lampert, D. Grün, Ingo Scholtes · 0 citations