Background.
Transcriptomic data show which genes are active in cells and tissues. Machine-learning and deep-learning methods use these data to classify samples, integrate different datasets, and predict biological properties and treatment response. In oncology, a major challenge is transferring patterns identified i...
I. A. Solovev, D. Golubev· Pharmacokinetics and Pharmac...· 0 citations
Introduction
. Intertumoral differences in biological response to radiation remain a major obstacle to the full personalization of radiotherapy. Radioresistance is driven by multiple factors, including DNA repair, hypoxia, metabolic reprogramming, and cancer stem cells, which renders the search for a single biomarke...
I. A. Soloviev, D. Golubev· Patient-Oriented Medicine an...· 0 citations
A critical translational synthesis of oncology databases and computational resources used to predict tumor radiosensitivity and chemosensitivity and shows homologous recombination deficiency in the context of DNA-damaging therapy and genomic-adjusted radiation dose as a research predictor of radiotherapy benefit is dem...
I. A. Solovev, D. Golubev· Real-World Data & Eviden...· 0 citations
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