Traversing the free-energy pathways of intricate biomolecular processes Enhanced simulation development and applications
G.Giubertoni, A. P. de Alba Ortíz, F. Bano et al.
· 0 citations
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AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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Lipid Nanoparticle Surface Engineering with Heparosan Polysaccharides Enhances mRNA Efficacy via Reduced Endosomal Retention
In this study, we developed a library of mRNA lipid nanoparticles (LNPs) containing clinically used ionizable lipids. We surface-modified these nanoparticles with heparosan polysaccharides and systematically compared their performance with conventional poly(ethylene glycol) (PEG)-modified formulations. Our heparosan (H...
Yu-Xin He, Lin Wang, Abigael P. Williams et al.
· ACS Nano · 0 citations