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Author

D. Daelemans

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Review Open access Oct 2026

CRISPR-based interrogation of alternative lengthening of telomeres: mapping dependencies, stress-buffering pathways, and therapeutic vulnerabilities.

These findings support a model in which ALT-positive cells rely not on a unique ALT-specific factor, but rather on stress-buffering mechanisms that prevent chronic telomeric dysfunction from triggering replication catastrophe and cell death, highlighting these pathways as promising candidates for further therapeutic in...

Ruth Lannoo, O. Bechter, D. Daelemans · 0 citations
Open access Aug 2026

Unravelling resistance mechanisms of oncolytic viruses in glioblastoma

These findings reveal shared and virus-specific cellular processes driving OV resistance in GBM, providing a basis for strategies to overcome resistance.

T. Deconinck, T. Dierckx, F. De Smet et al. · 0 citations

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