Open access
Jul 2026
Global Changes in Unproductive Splicing and NMD Efficiency in Tumors
A robust metric derived from splicing quantification in the RNA-seq data to measure NMD efficiency at a sample level is developed and a striking divergence of NMD efficiency in cancers is observed, suggesting that tumors partially erase the NMD signature of their tissue of origin.
L. Zavileyskiy, A. Mironov, D. D. Pervouchine
· Acta Naturae · 0 citations