Author

D. Cornec

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Open access Sep 2026

BiomiX 3.0: A user-friendly platform for democratized multi-omics integration with graph-based learning

Background Multi-omics integration has emerged as a powerful strategy to decode the molecular complexity of biological systems. However, the diversity of available methods, each designed with distinct assumptions, objectives, and computational requirements, makes method selection, usage and interpretation challenging f...

Iñigo Clemente-Larramendi, J. Gliozzo, Lourdes Velo-Suárez et al. · bioRxiv · 0 citations

Open access Aug 2025

Interferon-α–Driven Stratification of B Cell Reveals Metabolic Reprogramming of Double Negative, Naive and Transitional cell subsets and Refines Molecular Classification in Sjögren’s Disease

Sjögren’s disease (SjD) is a chronic autoimmune condition marked by lymphocytic infiltration of exocrine glands and production of autoantibodies such as anti-SSA/Ro, anti-SSB/La, and rheumatoid factor. B lymphocytes play a central role in disease pathogenesis, driving autoantibody production and glandular damage, and c...

C. Iperi, Akhiya Anilkumar Rekha, Gustav Arvidsson et al. · bioRxiv · 2 citations

Open access Jul 2026

FloREN: Decoding Immune Regulatory Networks through Interpretable Graph Transformer Patient Representations

A Framework for Learning Over REgulatory-Embedding Networks (FloREN), a supervised and interpretable sample representation method that enables improved sample stratification and biomarker discovery and supports downstream analyses that found specific immune network mechanisms in immune-mediated inflammatory diseases (I...

Iñigo Clemente‐Larramendi, S. Hillion, D. Cornec et al. · bioRxiv · 0 citations