Open access
Jul 2026
Structural dynamics of RNA polymerase II throughout the nucleotide addition cycle
These findings define a comprehensive structural and dynamic framework for RNAPII NAC, yielding a “molecular movie” of RNAPII in action and revealing a fundamental principle by which the enzyme balances speed and fidelity through coordinated conformational dynamics.
Gangshun Yi, Qing-Rong Li, H. Holmberg et al.
· Nature Communications · 1 citation