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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

D. Aguillón

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Open access Oct 2026

A-105: Early Cognitive and Behavioral Outcomes in Child Carriers and Non-Carriers: Preliminary Findings From the Longitudinal NeuroKids Autosomal Dominant Alzheimer’s Disease Study

Objective: Individuals carrying the Presenilin-1 (PSEN1) E280A mutation are nearly certain to develop autosomal dominant Alzheimer’s disease (ADAD) by their forties. Although presymptomatic differences have been observed in adults decades before symptom onset, the earliest divergence remains unknown. This ongoing lon...

Meredith C. Rowe, N. Londoño, Sarita Firstman Lamus et al. · 0 citations
Open access Aug 2026

Mechanisms of resilience to autosomal dominant Alzheimer’s disease via oligogenic modulation of rare variants in the entorhinal cortex

Two PSEN1 E280A carriers have presented extreme protection against autosomal dominant Alzheimer’s disease (ADAD), with over two decades of delay for dementia onset. One of them, a male heterozygous for the RELN-COLBOS protective variant showed increased neuronal density in the entorhinal cortex 1. We conducted a deep p...

Yassir El-Amri, N. Villalba-Moreno, Julia A. Urban et al. · 0 citations
Open access Sep 2026

Genomic Landscape of Early-Onset and Familial Latin American Parkinson’s Patients

By expanding the reported spectrum of disease-associated variants in a Latin American population, this work identified previously unreported or underrepresented variants that would likely be missed by array-based or targeted screening approaches and contribute to the characterization of EOPD and familial PD in Latin Am...

E. Waldo, H. M. Chaparro-Solano, M. Isayan et al. · 0 citations
Open access Jul 2026

Remote digital cognitive assessment in a trial‐ready Alzheimer's disease cohort: A scalable approach for early intervention studies

High‐frequency remote cognitive assessment is feasible, reliable, and valid in a relatively young international ADAD cohort, supporting its integration into early‐intervention studies.

A. Aschenbrenner, Hannah M. Wilks, Matthew S. Welhaf et al. · 1 citation
Open access Jul 2026

Associations among mild behavioral impairment, cognition, and brain pathology in preclinical autosomal dominant Alzheimer's disease

It is revealed that mild behavioral impairment symptoms may emerge before cognitive decline in ADAD and supports the MBI‐C as a tool for detecting early behavioral changes linked to AD pathology and identifying at‐risk individuals for clinical trials and early intervention.

Catarina Tristão-Pereira, D. Vásquez, Jorge Alcina et al. · 1 citation

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