Author

Cuizhen Zhu

2 papers indexed here

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Open access Sep 2026

Celecoxib Ameliorates Chronic Restraint Stress-Induced Depression-Like Behavior in Sprague-Dawley Rats

Introduction Chronic stress is associated with depressive-like behaviors, dysregulation of the hypothalamic-pituitary-adrenal axis, and changes in inflammatory signaling. Celecoxib is a selective cyclooxygenase-2 inhibitor that has been investigated as a potential adjunctive treatment for depression; however, its effec...

Yian Ling, Jing Li, Wan-Bin Liu et al. · Neuropsychiatric Disease and... · 0 citations

Open access Aug 2026

IL-1α and CRP as key inflammatory mediators linking neuropathic pain, anxiety, and depression in major depressive disorder

The findings highlight IL-1α and CRP as key inflammatory markers associated with the relationship between pain, anxiety, and depressive symptoms and suggest the potential relevance of inflammation-related pathways in the clinical assessment of pain within the context of MDD.

Cuizhen Zhu, Lin Cheng, Jian Cheng et al. · BMC Psychiatry · 0 citations