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Cristina Roseti

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Review Open access Jul 2026

At the Crossroads of Synapses and Signaling: The Role of LRRK2 in Neuronal Communication

How LRRK2-dependent trafficking mechanisms regulate key components of synaptic transmission, including glutamatergic and GABAergic receptors, as well as astrocytic transporters are examined, highlighting how disruption of these processes affects neurotransmitter clearance, receptor activation, and ultimately E/I balance.

Angela Di Iacovo, Chiara D’Agostino, Giulia Casoli et al. · 0 citations

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