Cristina Galán-Arcicollar

Bayesian joint modeling of longitudinal patient-reported outcomes and survival: an application to chronic obstructive pulmonary disease

Questionnaire-based patient-reported outcomes (PROs) are discrete, bounded and overdispersed, yet joint models relating them to survival may ignore these features or estimate both processes sequentially. We propose a Bayesian joint model combining a beta-binomial mixed-effects submodel with a Weibull proportional hazar...