Open access
Sep 2026
Small RNA profiling reveals inflammatory and mitochondrial changes in aging β cells and islet macrophages
Aging is associated with functional decline and senescence of pancreatic β-cells. Modulation of post-transcriptional mechanisms is a hallmark of aging. Here we analyze the small non-coding RNA (sncRNA) repertoire of FACS-sorted β-cells and islet-resident macrophages (iMACs) from 3-, 12-, and 22-month-old mice, and of...
C. Guay, Jérôme Perrard, Eleonora Mangano et al.
· Communications Biology · 0 citations