Author

Craig A. Goodman

2 papers indexed here

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Open access Sep 2026

β-hydroxy-β-methylbutyrate improves fast-twitch muscle function, histopathology and mitochondrial respiration in the D2.mdx dystrophic mouse.

This study is the first to demonstrate that HMB enhances in vivo and ex vivo muscle function, downstream mTORC1 signalling, and mitochondrial performance in the severe D2.mdx mouse model of Duchenne muscular dystrophy, supporting its potential as a therapeutic strategy for DMD.

Nicholas Giourmas, Hannah Lalunio, Memphis Calzoni et al. · Journal of Physiology · 0 citations

Open access Jul 2026

Sex-divergent skeletal muscle remodeling emerges early in cancer cachexia.

Results show that cachexia progression in this model is sexually dimorphic and skeletal muscle undergoes extensive remodeling before overt wasting and sex-divergent pre-cachectic windows that may guide early biomarker discovery and therapeutic strategies aimed at preventing progression and improving quality of life in...

Chris Karagiannis, Alastair A. E. Saunders, Rachel E. Thomson et al. · American Journal of Physiolo... · 0 citations