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Constance Fiocco

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Open access Oct 2026

Implementation of DPYD genetic testing at a safety net oncology clinic.

628 Background: DPYD gene variants are associated with severe, potentially fatal toxicity from fluoropyrimidines (5-fluorouracil and capecitabine). Approximately 4-8% of the population carries deleterious variants affecting dihydropyrimidine dehydrogenase (DPD) activity. In October 2025, the FDA issued a black...

Constance Fiocco, Sarita Mohanty, Jennifer J. Wu · 0 citations

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