Author

Connor P. Jewell

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Open access Sep 2026

Identification of Gβ5 Interactome Associated with Neuronal Development in Neuro-2a Cells through miniTurbo Proximity Labeling

The enriched phenotypes associated with the Gβ5 interactome in the results align with previously reported phenotypes of Gβ5 deficiencies.

Harrison J. McNabb, Jian-Hua Zhang, Connor P. Jewell et al. · ACS Omega · 0 citations

Open access Aug 2026

SV40 Large T antigen inhibits the host serine protease FAM111A through a zinc-dependent, cleavage-avoiding mechanism

The X-ray crystal structure of the FAM111A serine protease domain in complex with LT-C is reported, revealing the structural basis for direct inhibition of FAM111A and defining a zinc-dependent, cleavage-avoiding mechanism of protease inhibition that highlights an evolutionary arms race between SV40 and host antiviral...

Allison L. Welter, S. Dharavath, Yuka Machida et al. · bioRxiv · 0 citations