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Congliang Chen

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Aug 2026

CARM1: an epigenetic brake on cDC1-mediated antitumor immunity.

The underlying mechanism of tumor microenvironment-induced dysfunction of conventional type 1 dendritic cells (cDC1) remains unclear. Zhang et al. identify transforming growth factor β-driven coactivator-associated arginine methyltransferase 1 (CARM1) as an epigenetic inhibitor of cDC1 cross-presentation. CARM1 is a ce...

Congliang Chen, Xue-Tao Cao · 0 citations

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