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Clayton J. H. Brown

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Open access Oct 2026

Applications of OptoProfilin in Living Cells for the Imaging of Focal Adhesions and Stress-Associated Phenotypes

OptoProfilin, a genetically encoded single-component optogenetic biosensor derived from Profilin-1 fused to Cryptochrome 2 (Cry2) and mCherry, provides a convenient platform for investigating stress-associated cytoskeletal remodeling and biomolecular condensate formation.

Clayton J. H. Brown, R. M. Hughes · 0 citations

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