Clary B. Clish

Plasma metabolomic profiles associated with breastfeeding history and subsequent ovarian cancer risk.

BACKGROUND Breastfeeding reduces ovarian cancer risk, but the underlying biological mechanisms remain unclear. METHODS We examined the association between a previously reported metabolite-based breastfeeding score with incident epithelial ovarian cancer risk in case-control studies nested within the Nurses' Health St...

What's next for metabolomics?

Metabolomics has become a mainstream approach that examines the metabolic composition of biological systems in relation to their physiological and disease states. Using analytical techniques such as nuclear magnetic resonance spectroscopy and mass spectrometry, metabolomics enables detailed profiling of small molecules...

Systematic Integration of genomics with transcriptomics for the Study of Coronary Artery Disease and Subclinical Atherosclerosis